针刺镇痛的神经化学基础 第三卷 1997-2006 英文版
作者：韩济生
出版时间： 2008年版
内容简介：
《针刺镇痛的神经化学基础（Volume3）（1997-2006）》把最近10年（1987—1997年）来取得的科研成果加以系统整理，用英文发表，希望有助于增进医学界和生物学界对针刺镇痛原理的了解，这一项努力的目的不仅在于促进针灸的临床应用，更希望能吸引更多学者投入这一研究，必然会发现更多的可用于针刺疗法的适应症。药物依赖，特别是海洛因成瘾，很可能是这些适应症之一。
目录：
1OVERVIEW
1.1Acupunctureactivatesendogenoussystemsofanalgesia
1.2Acupunctureanesthesia（AA）versusacupuncture-assistedanesthesia（AAA）
1.3Electroacupuncture：mechanismsandclinicalapplication
1.4Acupunctureresearch&neurosciencedevelopment
1.5Traditionalandevidence-basedacupuncture：history，mechanisms，andpresentstatus
1.6Opioidandantiopioidpeptides：amodelofYin-Yangbalanceinacupuncturemechanismsofpainmodulation
1.7Acupuncture：neuropeptidereleaseproducedbyelectricalstimulationofdifferentfrequencies
1.8Heritabilityofnociception.HI.Geneticrelationshipsamongcommonlyusedassaysofnociceptionandhypersensitivity
1.9Theeffectofgenotypeonsensitivitytoelectroacupunctureanalgesia
2PEPTIDEANDNON-PEPTIDEOPIOIDAGONIST
2.1Discriminationbetweenpeptideandnon-peptideopioidagonistsonthetranscriptionofopioidreceptorsintwocelllines
2.2Inhibitionofthetranscriptionofuopioidreceptorbylong-termexposureofSHSY5Ycelllinetopeptideandnon-peptideopioidagonists
2.3Themetabolicevidenceofsynergisticeffectbetweenohmefentanyland[D-Pen2，D-PenS]enkephalinondifferentiatedSH-SY5Ycellsinhumans
2.4ThemetabolicevidenceofsynergisticinteractionbetweenDAMGOandDPDPEonundifferentiatedSH-SY5Ycells
3ACUTEPAIN
3.1Endomorphin-1mediates2Hzbutnot100Hzelectroacupunctureanalgesiaintherat
3.2Endomorphinandu-opioidreceptorsinmousebrainmediatetheanalgesiceffectinducedby2Hzbutnot100Hzelectroacupuncturestimulation
3.3Acupunctureandendorphins
3.4Effectsofsynchronousorasynchronouselectroacupuncturestimulationwithlowversushighfrequencyonspinalopioidreleaseandtailflicknociception
3.5DecreaseddynorphinA（1-17）inthespinalcordofspasticratsafterthecompressiveinjury
3.6Involvementofionotropicglutamatereceptorsinlowfrequencyelectroacupunctureanalgesiainrats
3.7Characteristicsofelectroacupuncture-inducedanalgesiainmice：variationwithstrain，requency，intensityandopioidinvolvement..
3.8Relationsbetweenbrainnetworkactivationandanalgesiceffectinducedbylowvs.highfrequencyelectricalacupointstimulationindifferentsubjects：afunctionalmagneticresonanceimagingstudy
3.9Modulationofcoldpaininhumanbrainbyelectricacupointstimulation：evidencefromMRI
3.10EvidencefrombrainimagingwithfMRIsupportingfunctionalspecificityofacupointsinhumans
3.11Modulationofpainsignalprocessingbyelectricacupointstimulation：anelectroencephalogramstudy
3.12Parallelpainprocessinginfreelymovingratsrevealedbydistributedneuronrecording
3.13Nociceptiveresponsesofanteriorcingulatecorticalensemblesinbehavingrats
3.14Differentialmodulationofnociceptiveneuralresponsesinmedialandlateralpainpathwaysbyperipheralelectricalstimulation：amultichannelrecordingstudytheanalysisofcerebralevokedpotentials
3.15Sliding-windowtechniquefor
3.16Codingofperipheralelectricalstimulationfrequencyinthalamocorticalpathways
3.17Acontrolledstudytoevaluatetheanalgesiceffectoftranscutaneouselectricnervestimulationonpost-operativepaininpatientsofcardiacoperation：patient-controlledanalgesiaastheevaluationcriterion
4CHRONICPAIN
4.1DecreasedGDNFmRNAexpressionindorsalspinalcordofunilateralarthriticrat
4.2Glialcellline-derivedneurotrophicfactorcontributestodelayedinflammatoryhyperalgesiainadjuvantratpainmodel
4.3Changeofvanilloidreceptor1expressionindorsalrootganglionandspinaldorsalhornduringinflammatorynociceptioninducedbycompleteFreundsadjuvantinrats
4.4Attenuationofmechanicalbutnotthermalhyperalgesiabyelectroacupuncturewiththeofopioidsinratmodelofchronicinflammatorypaininvolvement
4.5Repeated100HzTENSforthetreatmentofchronicinflammatoryhyperalgesiaandsuppressionofspinalreleaseofsubstancePinmonoarthriticrats
4.6Repeatedadministrationoflowdoseketamineforthetreatmentofmonoarthriticpainintherat
4.7Ketaminepotentiatestheeffectofelectroacupunctureonmechanicalallodyniainaratmodelofneuropathicpain
4.8Suppressionofneuropathicpainbyperipheralelectricalstimulationinrats：&-opioidreceptorandNMDAreceptorimplicated
4.9Hyperpolarization-activated，cyclicnucleotide-gatedcationchannels：rolesinthedifferentialelectrophysiologicalpropertiesofratprimaryafferentneurons
4.10EctopicdischargesfrominjurednervefibersarehighlycorrelatedwithtactileaUodyniaonlyinearly，butnotlate，stageinratswithspinalnerveligation
4.11Inhibitionofhyperpolarization-activatedcurrentbyZD7288suppressesectopicdischargeofinjureddorsalrootganglionneuronsinaratmodelofneuropathicpain
4.12Dynamicneuronalresponsesincorticalandthalamicareasduringdifferentphasesofformalintestinrats
……
5ANTI-OPIOIDPEPTIDESANDOPIOIDTOLERANCE
6DRUGDEPENDENCE
7PARKINSIONSDISEASE
8OBESITY
APPENDIX1SourceofPaper
APPENDIX2Acupunctureresearchispartofmylife





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